美国赛力克 Bcl-2靶点有哪些分子

Cat.No. Product Name Feedback 订购电话

S1001

ABT-263 (Navitoclax)

021-3376 6115
ABT-263 (Navitoclax) is a potent orally bioavailable SMI that is structurally related to ABT-737. ABT-263 disrupts Bcl-2 - Bcl-XL interactions with pro-apoptotic proteins.
 
S1002

ABT-737

021-3376 6115
ABT-737 is a pan-Bcl-2 inhibitor. IC50 values ranged from 192 nM (the pre-B cell line Hal-01) to <10 μM (Nalm-6, K562, and HL-60).
 
S1057

Obatoclax (GX15-070)

021-3376 6115
Bcl-2 homology domain-3 (BH3) mimetic,antagonize all antiapoptotic Bcl-2 family proteins (average IC50, 3 umol/L), including Mcl-1 (IC50, 2.9 umol/L) and Bfl-1 (IC50, 5 umol/L)
 
S1121

TW-37

021-3376 6115
TW-37 is a Bcl-2 protein family inhibitor with a Ki of 0.29 μM.

 

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