美国赛力克化学 mTOR靶点癌症肿瘤研究的分子有哪些?

Cat.No. Product Name Feedback 订购电话

S1555

AZD8055

  021-33766115
AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of 0.8 nM.
 
S1009

BEZ235 (NVP-BEZ235)

021-33766115
BEZ235 (NVP-BEZ235) is an inhibitor of PI3K and mTOR.p110, IC50<6nM.
 
S2406

Chrysophanic acid (Chrysophanol)

  021-33766115
Chrysophanic acid (Chrysophanol) is a EGFR/mTOR pathway inhibitor.
 
S1022

Deforolimus (Ridaforolimus)

021-33766115
Deforolimus (Ridaforolimus) is a small-molecule inhibitor of mTOR.
 
S1120

Everolimus (RAD001)

021-33766115
Everolimus (RAD001) also known as SDZ-RAD, Certican, Zortress, Afinitorm is TOR inhibitor available at Selleck with IC50 of 0.63 nM.
 
S1360

GSK1059615

021-33766115
GSK1059615 is a pan-PI3K reversible inhibitor,IC50:PI3Kα(0.4 nM), β (0.6 nM),γ (5 nM),δ (2 nM) and mTOR(12 nM).
 
S2658

GSK2126458 (GSK212) 

  021-33766115
GSK2126458 (GSK212) is a highly potent PI3K and mTOR inhibitor with an app Ki of 19 pM for PI3K.
 
S1226

KU-0063794

021-33766115
mTOR inhibitor, IC50 ~10 nM for mTORC1 and mTORC2, respectively.
 
S2624

OSI-027 

  021-33766115
OSI027 is a potent mammalian target of rapamycin (mTOR) kinase inhibitor.
 
S2238

Palomid 529 (P529) 

  021-33766115
Palomid 529 (P529) is a novel potent antitumour PI3K/Akt/mTOR inhibitor with a GI50 of <35 μM in the NCI-60 cell lines panel.
 
S1038

PI-103

021-33766115
PI-103 is a potent, cell-permeable, ATP-competitive PI3K family members inhibitor with IC50 of 2, 8, 20, 26, 48, 83, 88, 150 nM for DNA-PK, p110α, mTORC1, PI3-KC2β, p110δ, mTORC2, p110β, and p110γ, respectively.
 
S2628

PKI587 

  021-33766115
PKI-587 is a highly potent dual PI3K/mTOR kinase inhibitor with IC50 of 0.4 nM and <0.1 μM for PI3K-α and mTOR, respectively.
 
S2218

PP242

  021-33766115
PP242 is a novel potent and selective mTOR inhibitor with an IC50 of 8 nM.
 
S1039

Rapamycin (Sirolimus)

021-33766115
Rapamycin also known as Sirolimus & Rapamune is a mTOR inhibitor. Rapamycin Sirolimus inhibits cell motility by suppression of mTOR-mediated pathways.
 
S1044

Temsirolimus (Torisel)

021-33766115
Temsirolimus (Torisel) is a mTOR inhibitor.
 
S1266

WYE-354

  021-33766115
WYE-354 is a mTOR inhibitor with an IC50 of 5 nM.
 
S1523

XL765

  021-33766115
XL765 is a mixed mTOR/PI3k inhibitor with IC50 of 157, 39, 113, 9 and 43 nM for mTOR, p110α, β, γ and δ, respectively.

 

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