美国赛力克 p38 MAPK靶点有哪些分子

Cat.No. Product Name Feedback 订购电话

S1574

BIRB 796 (Doramapimod)

  021-33766115
BIRB 796 (Doramapimod) a small molecule of p38 MAPK inhibitor with Kd of 0.1 nM is available at Selleck.
 
S1494

LY2228820

  021-33766115
LY2228820 is a novel and potent p38MAPK inhibitor (the IC50 for p38αMAPK and p38βMAPK were 7 nM and 3 nM, respectively).
 
S1077

SB 202190

021-33766115
P38 MAP(mitogen activated protein) Kinase inhibitor.
 
S1076

SB 203580

021-33766115
SB 203580 is a potent inhibitor of LPS-induced cytokine synthesis in the human monocyte cell line THP-1 (IC50 = 50-100 nM).
 
S1527

Vinorelbine (Navelbine)

  021-33766115
Vinorelbine (Navelbine) is the first 5´NOR semi-synthetic vinca alkaloid and exerts its activity through the MAPK (p38) pathway with median IC90 and IC50 of 15.5 and 2.3 μM.
 
S6005

VX-702

  021-33766115
VX-702 is a P38 MAPK inhibitor , IL-6, IL-1β and TNFα (IC50 = 59, 122 and 99 ng/ml, respectively)
 
S1458

VX-745

  021-33766115
VX-745 is a lead anti-inflammatory candidate, p38 MAPK inhibitor (IC50=10 nM) for the treatment of Rheumatoid arthritis (RA).

 

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