美国赛力克化学 COX靶点有哪些分子?

 

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S1634

Acetaminophen

  021-33766115
Acetaminophen is a highly selective inhibitor of COX-2 and 6-keto-PGF1 alpha with IC50 of 302.3 mg/kg and 10 µM, respectively.
 
S2531

Asaraldehyde (Asaronaldehyde)

  021-33766115
Asaraldehyde (Asaronaldehyde; Asarylaldehyde; Gazarin; NSC 89299; 2,4,5-Trimethoxybenzaldehyde) is a selective COX-2 inhibitor.
 
S1903

Diclofenac

  021-33766115
Diclofenac is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively.
 
S1638

Ibuprofen (Advil)

  021-33766115
Ibuprofen (Advil) is a non-selective COX inhibitor with an IC50 of 0.33 mM.
 
S1645

Ketoprofen (Actron)

  021-33766115
Ketoprofen (Actron) is a non-selective NSAID with IC50 of 0.5 μM and 2.33 μM for human recombinant COX-1 and COX-2, respectively.
 
S1646

Ketorolac (Toradol)

  021-33766115
Ketorolac (Toradol) is a non-selective COX inhibitor with IC50 of 31.5 µM and 60.5 µM for human recombinant COX-1 and COX-2, respectively.
 
S1626

Naproxen (Aleve)

  021-33766115
Naproxen (Aleve) is a non-selective cyclooxygenase (COX) inhibitor with IC50 of 8.7 ± 0.23 mg/kg.
 
S1713

Piroxicam (Feldene)

  021-33766115
Piroxicam (Feldene) is a non-selective COX inhibitor with an IC50 of 6 mM.

 

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