化疗药物库列表,美国Selleck高特异性分子库/高通量筛选列表,赛导通生物科技现货供应

 

 

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化疗药物库 (96孔板)产品目录号. L1500

粉末:

剂量 价格

1mg/well ¥ 8883

2mg/well ¥ 14553

预溶在DMSO中:

剂量 价格

100μL/well (10mM solution) ¥ 5670

250μL/well (10mM solution) ¥ 9450

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描述&优势

40种化疗药物的独特集合,可用于高通量筛选和高内涵筛选 。

通过临床实验,生物活性和安全性得到验证。

其中一些化疗药物已经得到FDA批准,用于肿瘤和非肿瘤治疗。

结构多样,药效显著,可渗透细胞。

具有充分详细的结构说明,IC50值,及客户反馈资料。

NMR和HPLC技术保证产品高纯度。

产品详细信息

配制: 40种化疗药物制成冻干粉或预溶在DMSO溶液中。

96-孔板: 是

储存: -80°C 长期储存

稳定性: 6个月

发货: 蓝冰物流

包装: 惰性气体

化疗药物库目录册

如果您需要下载化疗药物库目录册(.xlxs和.SDF),请通过 info@selleckchem.com联系我们

化疗药物库全部组成

 

 

下载产品目录册及宣传资料

 

使用我公司Selleck产品的论文

Sorafenib induces apoptotic cell death in human non-small cell lung cancer cells by down-regulating mammalian target of rapamycin (mTOR)-dependent survivin expression

[Young-Sun Kim, Hyeon-Ok Jin et al. Biochemical Pharmacology. 2011 August;82:216-226 ]

Anti-myeloma activity of a multi targeted kinase inhibitor,AT9283, via potent Aurora Kinase and STAT3 inhibition either alone or in combination with lenalidomide.

[Loredana Santo, Teru Hideshima et al. Clin Cancer Res. 2011 May;17:3259-3271]

Molecular Characterization of c-Abl/c-Src Kinase Inhibitors Targeted against Murine Tumour Progenitor Cells that Express Stem Cell Markers

[Thomas Kruewel, Silvia Schenone et al. PLoS One. 2010 November;5]

Global lymphoid tissue remodeling during a viral infection is orchestrated by a B celllymphotoxin-dependent pathway

[Varsha Kumar, Elke Scandella et al. BLOOD. 2010 June;115:4725-4733]

Sunitinib deregulates tumor adaptation to hypoxia by inhibiting HIF-1α synthesis in HT-29 colon cancer cells

Hyun-Woo Shin, Chung-Hyun Cho et al. Biochemical and Biophysical Research Communications. 2010;398:205-211

查看其它分子库

L1100

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L1800

酪氨酸激酶抑制剂分子库

提供86种酪氨酸激酶抑制剂集合

L1300

FDA批准的原料药库

提供381种FDA批准的原料药集合

L1400

天然产物库

130种天然产物的集合

L1700

化合物库

提供703种具有生物活性化合物的集合

客户反馈数据

 

Data independently produced by Dr Helen Sadik of Johns Hopkins University

Capecitabine (Xeloda) purchased from Selleck

Cells were seeded in 96 well paltes, and then treated with the indicated concentration of Capecitabine for 48h. Cell survival was measured by a standarad MTT assay.

 

 

 

Data independently produced by Dr Helen Sadik of Johns Hopkins University

Carboplatin purchased from Selleck

A. MCF10A-Ras overexpressing a vector control or the gene of interest (GeneX), or MCF7 expressing a scramble or a siRNA for the geneX were treated with DMSO or with Carboplatin for 24h. Resistant colonies were allowed to grow for 2 weeks, and are then stained with Crystal Violet. B. Quantification of the results.

 

Data independently produced by Dr Helen Rizos from the university of Sydney

Imatinib Mesylate purchased from Selleck

A. Viability curve for the c-Kit mutant MelMS melanoma cell line treated with increasing concentrations of imatinib for 72h (relative to DMSO-treated controls; mean ± sd; n=3) B. MelMS melanoma cells were treated with 50nM imatinib for 24h. The effects on c-Kit, ERK and AKT activation were determined by immunoblotting.

 

Data independently produced by Dr Helen Sadik of Johns Hopkins University

Gemcitabine Hydrochloride (Gemzar) purchased from Selleck

Cells were seeded in 96 well paltes, and then treated with the indicated concentration of Gemcitabine for 48h. Cell survival was measured by a standarad MTT assay.

 

 

 

Data from [Cancer Cell 2011.June;19:1–13]

Rapamycin (Sirolimus) purchased from Selleck

Cooperative Effects of AR and mTOR Inhibition In Vitro and In Vivo (A) In vitro response of Pten null;Ar+ murine (CaP8) and human (LNCaP) prostate cancer cells to AR knockdown (sh-AR) or pharmacological inhibition of AR (MDV3100, 10 mM) with and without rapamycin (R: 1 nM) treatment (Sc, control sh oligo). (B and D) In vivo response to treatments with castration, MDV3100, rapamycin, or their combinations as measured by cell proliferation (Ki67+cells) and (C and D) tumor burden in Pb-Cre+;-PtenL/L and Pb-Cre+;PtenL/L:ArL/Y mutants. Scale bars represent 2 mm (C), 200 mm (D), and 75 mm (D, inset). Error bars represent mean ± SD.

 

Data from [Biochem Bioph Res Co 2010 June;398:205–211]

Sunitinib Malate (Sutent) purchased from Selleck

Sunitinib limits the colonial growth of HT-29 by downregulating HIF-1a. (A) The number and size of colonies formed in soft agar. The numbers of small colonies (<50 lm diameter) were not different among conditions of a serial concentration of sunitinib. On the contrary, large colonies (>50 lm diameter) dis

 

 

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